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Diplopia (Double Vision)

Diplopia refers to the perception of seeing two images of a single object and may have both ophthalmologic and neurologic origins. The condition can manifest as horizontal (side-by-side), vertical (over-under), or mixed double vision. Diplopia often affects balance, coordination, and reading ability, making it a critical symptom that requires thorough assessment.

Diplopia

Types and Presentation

Monocular Diplopia

  • Occurs when only one eye is affected.

  • The double vision persists when the healthy eye is covered but disappears when the affected eye is covered.

  • Typically caused by intraocular pathologies such as refractive errors, cataracts, corneal disease, or macular disease.

Binocular Diplopia

  • Appears when both eyes are open and resolves when one eye is covered.

  • Most often caused by extraocular muscle dysfunction or cranial nerve palsy, resulting in ocular misalignment.

  • The image of an object falls on the fovea of one eye and an extrafoveal area of the other, producing double vision.


Causes

Monocular Diplopia

  • Refractive errors

  • Cataract

  • Corneal disease (e.g., irregular astigmatism)

  • Macular degeneration or macular pathology

  • Lens displacement (e.g., luxation)

  • Psychogenic causes or dry eye syndrome

Binocular Diplopia

Neurological causes (most common):

  • Cranial nerve palsies (CN III, IV, VI)

    • Oculomotor nerve palsy: affects superior, medial, and inferior rectus, and inferior oblique muscles

    • Trochlear nerve palsy: affects superior oblique muscle

    • Abducens nerve palsy: affects lateral rectus muscle

Other causes:

  • Thyroid eye disease

  • Aneurysm

  • Diabetes mellitus

  • Brain or orbital tumor

  • Multiple sclerosis

  • Head trauma


Evaluation

A careful history and clinical examination are essential to distinguish between ocular pathology, cranial nerve lesions, and neuromuscular disorders.

  • Acute-onset diplopia may signal a serious underlying disorder.

  • Intermittent diplopia with ptosis and daily variation suggests myasthenia gravis.

  • Progressive diplopia may indicate tumor or aneurysm compression.


Monocular Diplopia

  • Ophthalmologic evaluation focusing on cornea, lens, and retina.

  • Pinhole test helps differentiate refractive errors from organic pathology.


Binocular Diplopia

  • Assess ocular alignment and identify potential extraocular muscle paresis.


Physiotherapy Examination

Observation

  • Inspect for redness, swelling, or discharge.

  • Ask the patient to look upward without moving the head to observe range of motion.


Tests

  • Red reflex test: Ophthalmoscope used to assess posterior eye segments.

  • Light reflex test: Evaluates corneal reflection symmetry.

  • Accommodation test: Focus shift between near and far targets.

  • Visual acuity: Snellen chart or finger counting.

  • Ocular motility test: Evaluate all gaze directions with head stable.

  • Cover test: Patient covers one eye and reports persistence of double vision.


Saccades and Pursuits

  • Saccades: Rapid eye movements controlled by the frontal eye field (Brodmann area 8).

  • Pursuits: Smooth tracking movements controlled by the parietal–occipital–temporal cortex.


Treatment

Medical Management

  • Depends on underlying cause:

    • Prismatic lenses to correct alignment

    • Surgical correction for muscle or nerve lesions

    • Medication for autoimmune or inflammatory causes


Physiotherapy Management

  • Eye muscle exercises, saccades, and pursuit training can aid recovery and coordination.

Saccade Exercises

  • Focus on points on a page for 1 second, then jump to the next.

  • Perform horizontally, vertically, and diagonally.

  • 3–5 rounds, 3–4 times daily.

Pursuit Exercises

  • Follow the thumb or a pen horizontally, vertically, and diagonally.

  • Gradually increase movement speed.


Summary

Diplopia is a clinically important symptom that may range from minor refractive errors to severe neurological conditions. Accurate diagnosis requires detailed history-taking, ocular examination, and neurological assessment. Physiotherapy plays a supportive role through observation, visual tests, and oculomotor training, while medical interventions target the underlying cause.


References

  1. Danchaivijitr C, Kennard C. Diplopia and eye movement disorders. Journal of Neurology, Neurosurgery & Psychiatry. 2004 Dec 1;75(suppl 4):iv24-31.

  2. Rucker JC, Tomsak RL. Binocular diplopia: a practical approach. The neurologist. 2005 Mar 1;11(2):98-110.

  3. Gjenomgått -Trukket

  4. Tsutsumi S, Nakamura M, Tabuchi T, Yasumoto Y, Ito M. An anatomic study of the the the inferior oblique nerve with high-resolution magnetic resonance imaging. Surgical and Radiologic Anatomy. 2013 Jul;35(5):377-83.

  5. Glisson CC. Approach to diplopia. CONTINUUM: Lifelong Learning in Neurology. 2019 Oct 1;25(5):1362-75.

  6. Sowka J. Neurogenic diplopia: paralysis of cranial nerves III, IV, and VI. Optometry Clinics: the Official Publication of the Prentice Society. 1996 Jan 1;5(3-4):53-76.

  7. Merino P, Fuentes D, de Liaño PG, Ordonez MA. Binocular diplopia in a tertiary hospital: aetiology, diagnosis, and treatment. Archivos de la Sociedad Española de Oftalmología (English Edition). 2017 Dec 1;92(12):565-70.

  8. Dinkin M. Diagnostic approach to diplopia. continuum: Lifelong Learning in Neurology. 2014 Aug 1;20(4):942-65.


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